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真核细胞存在一整套DNA损伤应答机制,包括细胞周期检验点的调控、DNA损伤的修复及DNA损伤诱导的凋亡。DNA双链断裂(DSBs)是最严重的D......
真核生物对维持基因组的稳定性及防止非整倍体的产生,有其一套完整的保护机制,即细胞周期调控、检验点调控以及对损伤DNA的修复。......
DNA double-strand-breaks (DSBs) are the most serious DNA damage, which can be repaired mainly by two pathways, namely ho......
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DNA double-strand breaks (DSBs) are the most serious form of DNA damage.In human cells,non-homologous end joining (NHEJ)......